Active, accessible, and assuming no prior knowledge: the ideal text for biologists encountering bioinformatics for the first time.\nAimed at a biological audience, it is ideal for those without detailed prior knowledge of programming who are encountering bioinformatics for the first time\nFrequent examples, self-test questions, problems, and exercises are incorporated throughout the text to encourage self-directed learning\nEmphasises the practical applications of the subject to a wide range of disciplines, such as molecular biology, medicine, forensic science and anthropology\nInvaluable information retrieval techniques and data calculations are covered to enable the reader to carry out their own online research\nOnline resources include data sets and Web-based problems, alongside guidance for answering the problems and exercises in the book\nNew to this edition\nA host of new material includes new content on next generation sequencing, function prediction, sequence assembly, epigenomics, the bioinformatics of gene editing, and the effects of single nucleotide variants\nGreater background information has been provided for advanced topics to ensure that a broad range of readers will have the necessary pre-requisite knowledge to understand them